Discusión: Actimel
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Viejo 23-sep-2008, 12:01   #59 (permalink)
krisnesh
Manciano Zoidberg
 
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Registrado: julio-2008
País: Argentina
Ocupación: Bioquímico
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Ciertos Lactobacilos, que se venden como cultivos (actimel, yogur ) si tienen buenas propiedades terapéuticas.

Siempre, es importante, revisar bibliografía de los temas, y que mejor que buscar en pubmed.com o nutrition.org, donde se pueden leer interesantes papers.

Se ha encontrado que actúa positivamente en el tratamiento del Helicobacater pylori, el cual es considerado como cofactor del desarrollo de úlceras y cáncer estomacal.
También se ha encotrado que disminuye ciertas alergias, asi como mejora ciertas enfermedades intestinales, como inflamaciones.

No deberíamos olvidar que , además , los lactobacilos son fuentes de Vitamina B12.


Como ejemplos transcribo estos:

Supplement: Effects of Probiotics and Prebiotics
Helicobacter pylori and Probiotics1,2

Drahoslava Lesbros-Pantoflickova3,*, Irène Corthésy-Theulaz4 and André L. Blum5

3 Department of Internal Medicine, Clinique Genolier, 1272 Genolier, Switzerland; 4 Nestlé Research Center, 1000 Lausanne, Switzerland; and 5 Division of Gastroenterology, University Hospital of Lausanne, 1011 Lausanne, Switzerland

Helicobacter pylori infection, a highly prevalent pathogen, is a major cause of chronic gastritis and peptic ulcer and a risk factor for gastric malignancies. Antibiotics-based H. pylori eradication treatment is 90% effective. However, it is expensive and causes side effects and antibiotic resistance. Probiotics could present a low-cost, large-scale alternative solution to prevent or decrease H. pylori colonization. A literature search of the MEDLINE database (1966–2006) has been performed selecting all in vitro, animal, and human fully published English-language studies dealing with H. pylori and probiotics. Probiotics had an in vitro inhibitory effect on H. pylori. Animal studies demonstrated that probiotic treatment is effective in reducing H. pylori–associated gastric inflammation. Seven of 9 human studies showed an improvement of H. pylori gastritis and decrease in H. pylori density after administration of probiotics. The addition of probiotics to standard antibiotic treatment improved H. pylori eradication rates (81% vs. 71%, with combination treatment vs. H. pylori–eradication treatment alone; 2test: P = 0.03). Probiotic treatment reduced H. pylori therapy-associated side effects (incidence of side effects: 23% vs. 46%, with combination therapy vs. H. pylori–eradication treatment alone; 2test: P = 0.04). No study could demonstrate the eradication of H. pylori infection by probiotic treatment. So long-term intake of products containing probiotic strains of probiotics may have a favorable effect on H. pylori infection in humans, particularly by reducing the risk of developing disorders associated with high degrees of gastric inflammation.

Supplement: Effects of Probiotics and Prebiotics
Antiallergic Effects of Probiotics1,2

Arthur C. Ouwehand*

Department of Biochemistry and Food Chemistry and Functional Foods Forum, University of Turku, 20014 Turku, Finland and Danisco Innovation, 02460 Kantvik, Finland

A considerable part of the Western population suffers from some form of allergy, and the incidence is still rising with no sign of an end to this trend. Reduced exposure to microbial allergens as a result of our hygienic lifestyle has been suggested as one of the possible causes. It has also been suggested that probiotics may provide safe alternative microbial stimulation needed for the developing immune system in infants. This idea is supported by the fact that allergic infants have been observed to have an aberrant intestinal microbiota. They were shown to have more clostridia and fewer bifidobacteria and, in addition, to have an adult-like Bifidobacterium microbiota. Clinical trials have shown that the standard treatment of infants with atopic eczema, extensively hydrolyzed infant formula, can be significantly improved through the addition of Lactobacillus rhamnosus GG or Bifidobacterium lactis Bb-12. It has also been shown possible to halve the incidence of allergy in at-risk infants through administration of L. rhamnosus GG to expecting mothers and subsequently to their infants during the first half-year of life. Many mechanisms have been proposed for these beneficial effects, ranging from improved mucosal barrier function to direct influences on the immune system. However, the exact mode(s) of action are not yet known. For the future, elucidation of these mechanisms will be an important target. Another important area will be the investigation of interactions between probiotics and other food components that influence allergies. This will enable optimization of probiotic use for the allergic subject.


The efficacy of probiotics in gastrointestinal disease

Kamiya T, Shikano M, Wada T, Sasaki M, Joh T.
Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences.

Probiotics are live microbial feed supplement which beneficially affects the host animals by improving its microbial balance. Probiotics have been used in the treatment of bacterial or viral induced acute intestinal infection. In recent years, some clinical studies have shown the therapeutic effects of probiotics in the treatment of chronic inflammatory bowel disease (IBD) or prevention of allergic disease. Evidence exists for therapeutic use of probiotics in acute infectious diarrhea, Clostridium difficile colitis and antibiotic-associated diarrhea. Their exact role in IBD, irritable bowel syndrome and prevention of cancer has not to be determined. This review summarized the data about probiotics in gastrointestinal diseases and examine the mechanisms of action related to their therapeutic effects.
PMID: 18616132 [PubMed - indexed for MEDLINE]
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Chely (23-sep-2008)